> Mixture of branched alkyl fatty acid esters
> Molecular structure engineered according to the lipid autospreading system of water fowl
> Colorless liquid, neutral odor
> INCI name: Cetearyl Ethylhexanoate, Isopropyl Myristate
PCL Liquid by Symrise is an ideal excipient designed for livestock pour-on treatment. It is a fatty acid ester which is a highly effective vehicle for the delivery of pour-on actives such as avermectins and milbemycins. This excipient was designed to provide excellent spread over the animal while enhancing active absorption through the skin.
The spreadability of an excipient on the skin is dependent on several factors: molecular weight, structure, volatility, and fatty character. As the molecular weight increases, the spreading ability of an excipient decreases. PCL Liquid was evaluated for its skin spreading factor which gives an indication of the ester’s spreading properties. PCL Liquid showed favourable characteristics linked to its spreading capabilities.
In addition, PCL Liquid is an excipient with excellent absorption properties. With the combination of excellent spreadability and good skin polarity, PCL Liquid can be a valuable part of the pour-on formulation.
– Provides excellent skin spreading
– Enhances API absorption
– Helps form water resistant films